“- Young Gru: Mom, someday, I'm going to go to the moon.
- Gru's Mom: I'm afraid you're too late, son. NASA isn't sending the monkeys anymore.”

Steve Carrell - Gru
Julie Andrews - Gru's Mom

“If I could ask God one thing, it would be to stop the moon. Stop the moon and make this night and your beauty last forever.”
Shannyn Sossamon - William Thatcher

“- David Kessler: I'm a werewolf.
- Nurse Alex Price: Are you alright?
- David Kessler: I don't know, I'll let you know the next full moon.”
David Naughton - David Kessler
Jenny Agutter - Nurse Alex Price

“Respect! I wrote a haiku about respect. And the moon!”
Adrienne Shelly - Stephanie

“- Lula Fortune: One of these days the sun's gonna come up and burn a hole clean through the planet like a giant electrical x-ray.
- Sailor Ripley: I wouldn't worry about that, Peanut. By then people'll probably be driving Buicks to the moon.”
Laura Dern - Lula Fortune
Nicolas Cage - Sailor Ripley