“- Bob Wiley: What are we doing?
- Dr. Leo Marvin: Death therapy, Bob. It's a guaranteed cure.”

Richard Stephen Dreyfuss - Dr. Leo Marvin
Bill Murray - Bob Wiley

“- William H. 'Billy the Kid' Bonney: Hey, Peppin. I see you got Charley Crawford down there with you.
- Sheriff George Peppin: Yeah, that's right, Bonney. We got a whole...
[Bonney goes to the window and shoots Charley Crawford]
- William H. 'Billy the Kid' Bonney: Hey, Peppin. Charley Crawford's not with you anymore.”
Emilio Estevez - William H. 'Billy the Kid' Bonney
Craig Erickson - Sheriff George Peppin

“Turtle. He was my best buddy. Then his rifle backfired and blew his face off. We all learned a valuable lesson about weapon maintenance that day.”

Kieran Culkin - Igby

“Now sometime before morning, I'm going to let off both barrels of this shotgun right at you. I don't know just what time it'll happen... whenever my finger gets to itching too much.”

Jean Arthur - Phoebe Titus

“You're gonna have a double hole blown clear through you. Maybe ten minutes, maybe two hours. All you have to do is sit comfortable until I think it's the right time.”

Jean Arthur - Phoebe Titus