“- Jimmy McGinty: A real man admits his fears. That's what I'm asking you to do here tonight. Fears... lets talk about them.
- Clifford Franklin: I'm scared of spiders, Coach.”
Gene Hackman - Jimmy McGinty
Orlando Jones - Clifford Franklin

“- James Andrews: They tried to kill you too?
- Charlie Chan: Spider does not spin web for single fly.”
Russell Hicks - James Andrews
Warner Oland - Charlie Chan

“- Peter Parker: Some spiders change colors to blend into their environment. It's a defense mechanism.
- Harry Osborn: Peter, what possibly makes you think I would want to know that?
- Peter Parker: Who wouldn't?”
Tobey Maguire - Peter Parker
James Franco - Harry Osborn

“I'm gonna come at you like a spider monkey!”
Grayson Russell - Texas Ranger Bobby

“- Deputy Pete Willis: They're not aliens, they're spiders mutated by contaminated waste!
- Harlan Griffith: That's probably a more logical explanation!”
Rick Overton - Deputy Pete Willis
Doug E. Doug - Harlan Griffith