“- Rodney: I'm getting whisker-whipped up here! Hey, this is cruel to animals!
- Dr. John Dolittle: One more word, and I'm letting you out! I'll leave you in the wild! With the real animals! See how much talk you do when squirrels are kicking your ass in!
- Rodney: Fine, then I'll just sing!”

Chris Rock - Rodney
Eddie Murphy - Dr. John Dolittle

“You know what's gonna happen to you? I am gonna march you over to the zoo and feed you to the yak.”
Dorothy Whitney - Mag Wildwood

“- Charlie Carbone: It's a continent, Louis. He can go very far.
- Louis Booker: I know it's a continent. I read the book.
- Charlie Carbone: Did you happen to read the chapter on not putting your jacket on a wild animal?
- Louis Booker: No, but I did read the chapter on how an aborigine can kill a white man with a twig. Do you want to see that one?”

Jerry O'Connell - Charlie Carbone
Anthony Anderson - Louis Booker

“If you do that to me one more time, you are glue!”

Dom DeLuise - Itchy Itchiford

“You are the great lover! The dark figure of her dreams! Come on darling, tell him. Tell him how grateful you are. Tell him how you always wanted to be his. Go on tell him. Tell him how you wait for him. Tell him how he's the most sensitive, the best you ever had. Tell him that you love him, that's what he wants to hear.”

Tony Goldwyn - Dr. William "Will" Rudolph