“- Clark Griswold: We could leave her here and the first phone we pass, we could call your Cousin Normie and he could come and get her, I guess.
- Ellen Griswold: That is the meanest, coldest...
- Clark Griswold: Well what do you want me to do? Call Federal Express?”

Chevy Chase - Clark Griswold
Beverly D'Angelo - Ellen Griswold

“- Champlain: 1,500 miles by canoe, in that country, at the beginning of the winter. Death is almost certain, Father Bourque.
- Father Bourque: Death is not always a great evil, Monsieur Champlain.
- Champlain: God should have made me a Jesuit. You have answers for everything.”
Jean Brousseau - Champlain
François Tassé - Father Bourque

“- Billie Jean: You ever been to Vermont?
- Lloyd: Sure, on ski trips.
- Billie Jean: Maybe we should go there tonight, all of us, hitchhike.
- Lloyd: You can't do that, not now, everybody knows you, they want to see you get the money.
- Billie Jean: They want to see us dead, remember Joan of Arc?”
Helen Slater - Billie Jean
Keith Gordon - Lloyd

- Wash: This landing is gonna get pretty interesting.
- Mal: Define "interesting".
- Wash: Oh God, oh God, we're all going to die?
Alan Tudyk - Wash
Nathan Fillion - Mal

“Did I miss 60B? Did I miss 60B? Did I miss 60B? Did I miss 60B?”
Orlando Bloom - Drew Baylor