“- J. Frank Parnell: One day my mind was full to bursting. The next day - nothing. Swept away. But I'll show them. I had a lobotomy in the end.
- Otto: Lobotomy? Isn't that for loonies?”
Fox Harris - J. Frank Parnell
Emilio Estevez - Otto

“Pascal is accused of treason, and if convicted faces the death penalty. He says in that eventuality he would like to donate his brain to the study of the causes of hypomanic schizophrenia.”

Trevor McDonald - Newscaster

“- Ygor: You're going to help him Doctor? You are giving him life?
- Ludwig Frankenstein: Yes but not for the purposes that you think Ygor. I'm giving him strength so that an operation may be successful.
- Ygor: An operation?
- Ludwig Frankenstein: Yes. I'm giving him another brain.”
Béla Lugosi - Ygor
Cedrick Webster Hardwicke - Dr. Frankenstein

“- Ygor: Whose brain?
- Ludwig Frankenstein: Kettering. A man of character and learning. The monster will cease to be an evil influence and become everything that is good.”

Béla Lugosi - Ygor
Cedrick Webster Hardwicke - Dr. Frankenstein

“- Ludwig Frankenstein: Your dream of power is over, Bohmer. You didn't realize his blood is the same type as Kettering's, but not the same as Ygor's. It will not feed the sensory nerves.
- The Monster: Bohmer! You played me a trick! What good is a brain without eyes to see? What good is a brain without eyes?”

Cedrick Webster Hardwicke - Ludwig Frankenstein
Lon Chaney Jr. - The Monster