- Janis Ian: God! See, at least me and Regina George know we're mean! You try to act so innocent like, "oh, I used to live in Africa with all the little birds, and the little monkeys"!
- Cady Heron: You know what! It's not my fault you're like, in love with me, or something!
Lizzy Caplan - Janis Ian
Lindsay Lohan - Cady Heron

“- Frank Drebin: Hey! The missing evidence in the Kelner case! My God, he really was innocent!
- Ed Hocken: He went to the chair two years ago, Frank.”
Leslie William Nielsen - Frank Drebin
George Kennedy - Ed Hocken

“- Justice Wylie: You believe she's innocent?
- Frederick Aiken: I don't know. But if we don't get a proper trial, we never will.”
John Cullum - Justice Wylie
James McAvoy - Frederick Aiken

“Innocence can be hell.”
Lindsay Duncan - Dolphin Blue

“- Alan Dershowitz: I'm not a hired gun. I've got to feel there's some moral or constitutional issue at stake.
- Claus von Bülow: But I'm absolutely innocent, and my civil liberties have been egregiously violated!
- Alan Dershowitz: I've got two black kids facing the electric chair for a crime they did not commit. They are innocent.”
Ron Silver - Alan Dershowitz
Jeremy Irons - Claus von Bülow