“- Cruella De Vil: I want the job done tonight!
- Horace: How're we gonna do it?
- Cruella De Vil: Any way you like. Poison them. Drown them. Bash them in the head. You got any chloroform?”
Betty Lou Gerson - Cruella De Vil
Frederick Worlock - Horace

“- Lasky, Guard at Walleyworld: Has your father ever killed anyone?
- Rusty Griswold: Just a dog. Oh and my Aunt Edna.”
John Candy - Lasky, Guard at Walleyworld
Anthony Michael Hall - Rusty Griswold

- Cousin Avi: Look in the dog.
- Bullet-Tooth Tony: What do you mean "look in the dog"?
- Cousin Avi: I mean open him up.
- Bullet-Tooth Tony: It's not as if it's a tin of baked beans! What do you mean "open him up"?

Dennis Farina - Cousin Avi
Vinnie Jones - Bullet-Tooth Tony

“- Policeman with dog: You people are ought to stay back! Killer here loves to bite!
- Maximillian: So do I!”

Eddie Murphy - Maximillian

“- Drillbit Taylor: You'd be surprised, anything can be turned into a weapon of mayhem or destruction.
- Emmit: Even a puppy?
- Drillbit Taylor: Especially a puppy. The Germans used em' in World War I. De Hundin Schtorman, Lightning Dog. They'd attach dynamite to them.”
Owen Wilson - Drillbit Taylor
David Dorfman - Emmit