“- Richard Thorn: Damien was not affected by the gas.
- Ann Thorn: We can be thankful for that.
- Richard Thorn: Why all the other boys and not Damien?
- Ann Thorn: I don't understand. What did the doctor say?
- Richard Thorn: The tissue tests he made indicate that Damien has a different cell structure.
- Ann Thorn: Different?”
William M. Holden - Richard Thorn
Lee Grant - Ann Thorn

“Why do you bother helping people, huh? It doesn't do any good.”

Matt Dillon - Dallas Winston

“- Rick Gassko: Diagnoses?
- Dr. Stan Gassko: Medically speaking?
- Rick Gassko: Yes.
- Dr. Stan Gassko: Whacked out of his brains on drugs.”
Tom Hanks - Rick Gassko
William Tepper - Dr. Stan Gassko

“- Terry Macy, State Pagent: Somebody call a doctor!
- Colleen Douglas, State Pagent: A doctor? Somebody call a priest!”

Mo Gaffney - Terry Macy, State Pagent
Nora Dunn - Colleen Douglas, State Pagent

“- Steven M. Kovacs: You know, my brother is a speech therapist.
- The Cable Guy: Tho?”
Matthew Broderick - Steven M. Kovacs
Jim Carrey - The Cable Guy